Clinical Research Nurses

Clinical research nurses earned salaries that ranged from $61,000 to $113,000 or more in 2025, according to PayScale.com. They earned average salaries of $79,547. Clinical research nurses also earned bonuses that ranged from $497 to $8,000. The American Nurses Association says that average salaries for clinical research nurses are higher than the average for registered nurses, with these specialists earning $90,000 to $100,000 per year on average. GlassDoor.com reports that clinical research nurses earned salaries that ranged from $82,000 to $117,000 or more in 2025.

Benefits for nurses depend on the employer; however, they usually include such items as health insurance, retirement or 401(k) plans, and paid vacation days.